HLH- lesson one

I am a decently smart person and this diagnosis is difficult to understand in its pathology. I will try to explain it the best that I can. Let's look at the name, it tells a lot: Hemophagocytic- latin for "eating blood" Lymphohistiocytosis- lymph- part of the immune system,   histio- histiocytes- the type of cell …

Ladies and Gentlemen we have a winner…

Pathology report from Pittsburgh: The enlarged spleen with activated macrophages, and fairly extensive erythrophagocytosis, with a high intermixed content of CD3+ lymphocytes is a pattern seen in hemophagocytic lymphohistiocytosis (HLH) and other forms of macrophage activation syndrome, which is correlated with the patient's history of fevers and cytopenias. Tendencies of HLH- hemophagyocytic lymphohistiocytosis. Hard to …